General Description of the SAFE Strategy Against Trachoma The provided report summarizes the implementation of the SAFE strategy against trachoma during 2023. It contains estimations of the global population at risk of blindness from trachoma based on district-level data submitted to WHO by national programs. Summarizing the epidemiological situation in this manner is complex due to potentially up to three serial prevalence estimates being valid for a district within a single calendar year. To prevent misinterpretations and calculation errors, the highest estimated trachomatous inflammation (TF) prevalence for each district in a calendar year is used to generate a rolling maximum prevalence estimate for the period from January 1 to December 31, 2023. These figures serve as denominators for calculating intervention coverage. Additionally, summaries based on district-level prevalence estimates held in the GET2020 database as of April 15, 2024, are included to provide the most current information on progress toward global elimination of trachoma as a public health problem. The point prevalence picture for April 15, 2024, can be compared with that for April 25, 2023.Progress Report on the Elimination of Trachoma Trachoma, a preventable blinding disease, has been a major public health concern in many developing countries. The World Health Organization (WHO) has set a goal to eliminate trachoma by 2025. According to a recent progress report published by the WHO, significant progress has been made towards this goal. In 2022, 21 countries were validated as having eliminated trachoma as a public health problem. This brings the total number of countries that have achieved elimination to 32. The progress is attributed to the implementation of the SAFE strategy, which includes surgery to correct eyelid deformities, antibiotics to treat bacterial infections, facial cleanliness to prevent reinfection, and environmental improvements to promote sanitation. However, challenges remain in some areas. In 2022, an estimated 156 million people in 45 countries were still at risk of trachoma. The WHO has identified these countries as priority areas for intervention. The report emphasizes the need for continued efforts and collaboration among governments, health organizations, and communities to achieve the goal of eliminating trachoma by 2025. This includes scaling up prevention and treatment measures, strengthening surveillance systems, and raising awareness about the disease. By working together, we can ensure that everyone has the opportunity to live a life free from the devastating effects of trachoma.